Below you will find publications concerning triage, diagnosis using biomarkers and Medical treatment after exposure to Chemicals that affect lung functions or other organs. The publications are grouped into: Irritant gases, Cyanide, Chemical Warfare Agents and Triage.
Exposure to irritant gases can result in acute and chronic effect. The projects aim at 1) identifying biomarkers that can be used to identify if exposed individuals are at risk of developing chronic injuries and 2) for various treatments examine if an early medical intervention can reduce such damages.
Up to 80% of all deaths in fires are estimated to be due to exposure of fumes. Carbon monoxide is probably the most important, but evidence suggests that hydrogen cyanide, HCN, is a strong contributor. Although access to antidotes, people with symptoms of exposure to fire fumes are rarely treated for cyanide poisoning. Ths may be due to lack of an easy and rapid method for diagnosis. The project studied if a rapid method for diagnosing cyanide poisoning could be developed by measuring levels in exhaled are for use on-site by first responders.
Reports describing research and new understanding of chemical warfare agent toxicity and medical countermeasures are given below.
Rapid and accurate triage of affected individuals is of crucial importance for the medical management at large scale chemical exposures.